International MS Genetics Consortium

The International MS Genetics Consortium (IMSGC) was formed in 2003 with the aim of adopting a more collaborative approach to the challenge of identifying all the inherited risk factors for MS. The IMSGC uses large-scale whole genome association studies to identify the genes that play a part in the development and progression of multiple sclerosis.  The HNDC coordinates the IMSGC activities.


  • Combined resources of 25 research groups from 14 countries
  • Monthly conference calls
  • DNA collected from 20,000 subjects
  • Shared informatics platform with billions of data points


Adrian Ivinson, Harvard NeuroDiscovery Center

Sandra D’ Alfonso, A. Avogadro University, Italy

Philip De Jager, Brigham & Women’s Hospital

Diana Miclaus, Inflammgen, Canada

Bertrand Fontaine, Faculté de la Pitié Salpêtrière, France

Bernhard Hemmer, Leibniz-Rechenzentrum, Germany

Roland Martin, Inst Neuroimmunology & Clinical MS Research, Germany

Janna Saarela, Institute for Molecular Medicine, University of Helsinki, Finland

Annette Oturai, Region Hovedstaden, Demark

Tomas Olsson, Karolinkska Institutet, Sweden

An Goris, Katholieke Universiteit Leuven, Belgium

Lisa Barcellos, University of California, Berkeley

Rogier Q Hintzen, European School of NeuroImmunology, The Netherlands

Filippo Martinelli, Scientific Institute and University Ospedale San Raffaele, Italy

Frauke Zipp, Johannes Gutenberg-University Medicine, Germany

Peggy Pericak-Vance and Jacob McCauley, University of Miami

Stephen Hauser and Jorge Oksenberg, University of California, San Francisco

Luisa Bernardinelli, Alastair Compston, and Stephen Sawcer, Univer­sity of Cambridge, UK

Hanne Harbo, University of Oslo, Norway

John Rioux, University of Montreal, Canada

Manuel Comabella, Vall d’ Hebron Research Institute, Spain

Chris Cotsapas and David Hafler, Yale University

Bruce Taylor, University of Tasmania, Australia

Manuel Comabella, Vall d’ Hebron Research Institute, Spain

Allison R Baker and Jonathon Haines, Vanderbilt University

Aarno Palotie, Wellcome Trust Sanger Institute, UK

David Booth and Graeme Stewart, University of Sydney, Australia


For more information, click here.

See also: HNDC Programs